Clinical studies.
Clearer context.

Case study: The patient, a 16-year-old quarter horse gelding, suffered a large necrotic wound to the right lateral hock and calcanean bursa following a severe episode of lymphangitis and cellulitis. The wound was initially treated aggressively with antibiotics, administered systemically and by regional limb perfusion. Peptide therapy was initiated after 6 days following concerns over marked tissue loss and communication with deep synovial structures.

Treatment: Daily subcutaneous injection of BPC-157/TB-500 for 40 days starting 2/23/26. Systemic antibiotics. Weekly bandage changes through 3/9/2026.

Reported outcome: Following initiation of peptide therapy, the wound showed increased production of healthy, uniform granulation tissue with a notable reduction of discharge. The patient remained comfortable and the edematous swelling of the RH improved each week during therapy. Following 40 days of peptide therapy, the large cavity left by the loss of necrotic and infected soft tissue had granulated to the level of the surrounding skin.

Case study: 12-year-old Lusitano gelding used for dressage that initially presented with grade 1.5/5 right forelimb lameness due to superficial flexor tendinopathy. Initial treatment consisted of ultrasound-guided PRP and A2M injections followed by a structured rehabilitation protocol. Follow-up ultrasound exam showed resolution of the lesion, and the horse underwent a gradual return to full work.

Clinical course: Unfortunately, the horse experienced intermittent episodes of lameness associated with localized heat and swelling of the affected tendon that were consistent with ultrasound evidence of inflammation. The episodes improved with rest but showed a tendency to recur when the horse resumed full work intensity.

Treatment: Peptide therapy was initiated to address the recurrent nature of the injury, with subcutaneous injections of BPC-157/TB-500 given 5 days per week for 6 months.

Reported outcome: Since initiating peptide therapy, the horse has maintained full dressage training without recurrence of clinical signs. No further episodes of tendon-associated lameness, heat, or sensitivity have been observed. Recheck ultrasound examination shows normal collagen fiber alignment and minimal subcutaneous fibrosis associated with the RF SDFT.

Case study: The patient, a 19-year-old mustang gelding used for dressage, was evaluated for grade 2/5 lameness of the left hind. Ultrasound examination revealed marked synovitis of the medial femorotibial joint and an acute tear of the medial meniscus.

Treatment: Single injection of the left hind femorotibial joint with PRP. Daily subcutaneous injection of BPC-157/TB-500 for 40 days starting 1/6/26.

Reported outcome: The patient showed marked improvement of left hind lameness which was verified using objective gait analysis (Sleip). Repeat ultrasound examination showed significant improvement of the medial femorotibial joint and medial meniscus.

Case study: 11-year-old KWPN gelding jumper diagnosed with severe desmopathy of the right front lateral suspensory ligament branch causing grade 2/5 lameness.

Treatment: Electrohydraulic extracorporeal shockwave and daily subcutaneous injection of BPC-157/TB-500 for 40 days starting 10/23/25.

Reported outcome: Follow-up exam on 12/2/2025 showed significant improvement of RF lameness using Sleip objective gait analysis and marked improvement of the ultrasound appearance of the RF lateral suspensory ligament branch.

Case study: 18-year-old Warmblood gelding used for dressage treated for non-healing wounds over the lateral aspect of both front fetlocks.

Treatment: Surgical debridement (9/4/25 and 10/23/25), antibiotics, Phovia fluorescent light therapy, consistent bandaging, and multiple topical creams with minimal improvement. Started daily subcutaneous injections of BPC-157/TB-500 on 10/30/25.

Reported outcome: Marked improvement of wound size, granulation tissue uniformity, discharge quantity, and swelling throughout 40-day course of peptide therapy.